High sensitivity, broad range lactate detection with graphene sensor
Graphenea proudly announces that our graphene has been used in a high-sensitivity, broad-range lactate detector. The graphene-based sensor for lactate detection has a sensitivity of 100 pM and a range of detection up to 200 mM, that is, 12 orders of magnitude. The sensor also has high accuracy and rapid response times.
The active component of the lactose sensor is a CVD graphene device made in our Graphene Foundry, via the GFAB service, for Nanomolar, a spin-off of the National University of Singapore (NUS). Researchers from NUS recently published a paper detailing the results of lactose detection with the sensor. Lactate levels are related to a person’s oxygenation state, which is related to blood circulation. Hence, lactate sensors can be an important tool especially important for patients requiring critical care monitoring due to respiratory and cardiological issues. Two types of electrochemical lactate sensors were demonstrated, including bare and functionalized graphene.
Image: Graphene lactate detector. From Tkachev et al, Med Devices Diagn Eng 6 (2024).
Graphene devices can be excellent biosensors, with usage spanning across clinical science, sport science, medtech and point-of-care diagnostics. A number of our customers use our CVD graphene devices for scientific and commercial sensing purposes. It has been shown before that graphene biosensors can outcompete industry-leading ELISA and Simoa tests for point-of-care diagnostics of a biomarker for neurological diseases. Graphene has also been used as an immunosensor, enzyme, DNA, protein, glucose and bacteria sensor, among other biosensing applications.
The use of graphene in biosensing stems from a multitude of favourable properties of the material. The 2D nature of graphene in itself provides intrinsic advantages, because the entire material volume acts as a sensing surface. Furthermore, graphene provides excellent mechanical strength, biocompatibility, thermal and electrical conductivity, compactness, and potentially low cost.
Graphenea continues to work with customers to create devices for any desired application, in particular through the GFAB service and the multiproject wafer runs.